Wednesday, 23rd September 2020 - 7:33 am

Dr. Ayaluru Murali

Assistant Professor

Centre for Bioinformatics

About
Research Area

Our group identifies and works on a problem where bioinformatics plays key role. Our research uses several techniques including single particle analysis combined with bioinformatics with the use of other biochemical/biophysical tools as required. Our lab members work as a team with periodic review meetings, group discussions, literature reviews etc. I believe in the saying “teaching and research should go hand in hand” and hence teaching is given equal importance along with advancing research. “Work to your satisfaction rather than mere publishing” is our lab mission statement. We adopt “Quality not quantity” as our motto while publishing research papers.

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Research Guidance

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Teaching Experience

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Publications

Notable Publications

The highly efficient T7 RNA polymerase: a wonder macromolecule in biological realm S Borkotoky, A Murali International journal of biological macromolecules 118, 49-56 (2018)

An in-silico glimpse into the pH dependent structural changes of T7 RNA polymerase: a protein with simplicity S Borkotoky, CK Meena, GM Bhalerao, A Murali Scientific reports 7 (1), 1-12 (2017)

Insight into virus encapsulation mechanism through in silico interaction study between coat protein and RNA operator loops of Sesbania mosaic virus CK Meena, S Borkotoky, A Murali Molecular BioSystems 12 (6), 1996-2009 (2016)

Modeling of alcohol oxidase enzyme of Candida boidinii and in silico analysis of competitive binding of proton ionophores and FAD with enzyme MW Khan, A Murali Molecular BioSystems 13 (9), 1754-1769 (2017)

Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle M Gangloff*, A Murali*, J Xiong, CJ Arnot, AN Weber, AM Sandercock, ... Journal of Biological Chemistry 283 (21), 14629-14635 (2008) (* equal contribution)

Awards & Achievements​

Best Teacher recipient from Pondicherry University (Three times)

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